

However, the 20-40 mL/kg bolus was thought to be relatively conservative in the presence of what appeared to be septic shock and by any account these results are surprising. Criticisms of this study include a protocol change (which increased the amount of the fluid boluses) midway through the study, lack of control or documentation of fluid management after the first hour, unavailability of monitoring data, and lack of advanced hemodynamic monitoring. Mortality at 4 weeks was 12.2%, 12.0%, and 8.7%, respectively The primary outcome, death at 48 hours mortality was 10.6%, 10.5%, and 7.3% in the albumin-bolus, saline-bolus, and control groups, respectively. The perils of giving critically-ill patients arbitrary amounts of fluid without advanced monitoring (see section on modern fluid management below) was recently hilighted by the FEAST Trial, which included 3141 febrile pediatric patients with impaired perfusion (defined as capillary refill > 3 seconds, a lower-limb temperature gradient, “weak” radial-pulse volume, or severe tachycardia ) and randomized them to 20-40 mL/kg of normal saline, albumin, or no bolus on hospital admission. Danger Associated with Arbitrary Fluid Administration Remember to add up lap pads (100-150 cc each) and 4x4s (10 cc each). Step 4: Adjust for Unanticipated Fluid LossesĪ common recommendation is to give 3 cc of crystalloid for every 1 cc of blood loss. Step 3: Calculate Anticipated Surgical Fluid Lossesīased on patient’s weight and anticipated tissue trauma. Step 2: Calculate Ongoing Maintenance Requirementsīased on patient’s weight, using the same 4/2/1 rule as used to calculate preoperative maintenance requirements. Estimated maintenance requirements follow the 4/2/1 rule: 4 cc/kg/hr for the first 10 kg, 2 cc/kg/hr for the second 10 kg, and 1 cc/kg/hr for every kg above 20. Simply multiply the maintenance fluid requirements (cc/hr) times the amount of time since the patient took PO intake. Step 1: Calculate Preoperative Fluid Losses Furthermore, consider titrating fluid requirements to physiologic measures (ex. Calculating Fluid Requirementsįluids must be given based on an estimation of the following – fluid losses prior to start of anesthesia, maintenance requirements, normal fluid losses that occur during surgery, and response to unanticipated fluid (blood) loss. IT IS PRESENTED HERE FOR HISTORICAL INTEREST ONLY AND IS NOT RECOMMENDED. The “Classic” (read: outdated) approach to management of fluids in the perioperative setting involved trying to predict the amount of fluids needed based on a the duration and severity of a particular operation and empirically replacing fluids based on these estimates. If you have any trouble or suggestions email us at extension uses Google Analytics to collect extension usage statistics to help improve user experience.Approaches to Fluid Management The “Classic” Approach to Fluid Management

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